Publications
Bevandić J, Chareyron L, Bachevalier J, Cacucci F, Genzel L, Newcombe N.S, Vargha-Khadem F, Ólafsdóttir F. Episodic memory development: Bridging animal and human research. Neuron (in press) 2024.
Muessig L, Ribeiro Rodrigues F, Bjerknes T, Towse B, Barry C, Burgess N, Moser E, Moser M, Cacucci F, Wills T.J. The influence of environment geometry on subiculum boundary vector cells in adulthood and early development. Nature Communications, (in press) 2023.
Yang X, Cacucci F, Burgess N, Wills T.J, Chen G Visual boundary cues, alone, can anchor place and grid cells in virtual reality bioRxiv 2023. 564224.
Muessig L, Ribeiro Rodrigues F, Bjerknes T, Towse B, Barry C, Burgess N, Moser E, Moser M, Cacucci F, Wills T.J. The influence of environment geometry on subiculum boundary vector cells in adulthood and early development. bioRxiv 2023. 536690
Poulter S, Lee SA, Dachtler J, Wills T.J, Lever C. Vector trace cells in the subiculum of the hippocampal formation. Nat Neurosci. 2021 Feb;24(2):266-275.
Vargha-Khadem F, Cacucci F. A brief history of developmental amnesia. Neuropsychologia. 2021 Jan 8; 150:107689.
Cacucci F, Vargha-Khadem F. Contributions of nonhuman primate research to understanding the consequences of human brain injury during development. Proc Natl Acad Sci USA. 2019 Dec 26; 116(52):26204-26209.
Laurenz Muessig, Michal Lasek, Isabella Varsavsky, Francesca Cacucci & Thomas J. Wills Coordinated emergence of hippocampal replay and theta sequences during post-natal development
Elizabeth J Durkin, Laurenz Muessig, Tanja Herlt, Michael J Lumb, Ryan Patel, Philip Thomas, Damian P. Bright, Rachel Jurd1, Stephen J Moss1, Anthony H. Dickenson, Francesca Cacucci & Trevor G Smart Brain neurosteroids are natural anxiolytics targeting α2 subunit γ-aminobutyric acid type-A receptors
Korotkova, T., Ponomarenko, A., Monaghan, C., Poulter, S., Cacucci, F., Wills, T. J., . . . LEVER, C. (2018). Reconciling the different faces of hippocampal theta: the role of theta oscillations in cognitive, emotional and innate behaviours. Neuroscience and Biobehavioral Reviews. doi:10.1016/j.neubiorev.2017.09.004
Bassett, J. P., Wills, T. J., & Cacucci, F. (2018). Self-Organized Attractor Dynamics in the Developing Head Direction Circuit. Current biology: CB. doi:10.1016/j.cub.2018.01.010
Chen, G., King, J. A., Lu, Y., Cacucci, F., & Burgess, N. (2018). Spatial cell firing during virtual navigation of open arenas by head-restrained mice. eLife. doi:10.7554/eLife.34789
Cacucci, F., Salinas, P., & Wills, T. J. (2017). Hippocampus: Activity-Driven Maturation of Neural Circuits for Navigation. Current biology : CB, 27 (11), R428-R430. doi:10.1016/j.cub.2017.04.006
Tan, H. M., Wills, T. J., & Cacucci, F. (2017). The development of spatial and memory circuits in the rat. WILEY INTERDISCIPLINARY REVIEWS-COGNITIVE SCIENCE, 8 (3), UNSP e1424. doi:10.1002/wcs.1424
Chen, G., Manson, D., Cacucci, F., & Wills, T. J. (2016). Absence of visual input results in the disruption of grid cell firing in the mouse. Current Biology.
Muessig, L., Hauser, Wills, T. J., & Cacucci, F. (2016). Place cell networks in pre-weanling rats show associative memory properties from the onset of exploratory behaviour. Cerebral Cortex.
Marzo, A., Galli, S., Lopes, D., McLeod, F., Podpolny, M., Segovia-Roldan, M., . . . Salinas, P. C. (2016). Reversal of Synapse Degeneration by Restoring Wnt Signaling in the Adult Hippocampus. Current Biology. doi:10.1016/j.cub.2016.07.024
Muessig, L., Hauser, J., Wills, T. J., & Cacucci, F. (2015). A Developmental Switch in Place Cell Accuracy Coincides with Grid Cell Maturation. NEURON, 86 (5), 1167-1173. doi:10.1016/j.neuron.2015.05.011
Tan, H. M., Bassett, J. P., O'Keefe, J., Cacucci, F., & Wills, T. J. (2015). The Development of the Head Direction System before Eye Opening in the Rat. CURRENT BIOLOGY, 25 (4), 479-483. doi:10.1016/j.cub.2014.12.030
Mussig, L. (2013). Sensory integration in the hippocampal formation of pre- and post-weanling rats (Doctoral dissertation). University College London.
Wills, T. J., Muessig, L., & Cacucci, F. (2013). The Development of Spatial Behaviour and the Hippocampal Neural Representation of Space. Philosophical Transactions of the Royal Society of London: Biological Sciences.
Wills, T. J., & Cacucci, F. (2013). The development of the hippocampal neural representation of space. Current Opinion in Neurobiology, 24 (C), 111-119. doi:10.1016/j.conb.2013.09.006
Cacucci, F., Muessig, L., Hauser, J., & Wills, T. J. (2013). The role of environmental boundaries in the ontogeny of the hippocampal neural code for space.
Wills, T. J., Barry, C., & Cacucci, F. (2012). The abrupt development of adult-like grid cell firing in the medial entorhinal cortex. Front Neural Circuits, 6, 21-?. doi:10.3389/fncir.2012.00021
Muessig, L., Hauser, J., Wills, T. J., & Cacucci, F. (2012). The post-natal development of sensory integration in place cells of pre-weanling rats.
Stewart, S., Cacucci, F., & Lever, C. (2011). Which memory task for my mouse? A systematic review of spatial memory performance in the Tg2576 Alzheimer's mouse model. J Alzheimers Dis, 26 (1), 105-126. doi:10.3233/JAD-2011-101827
Wills, T. J., Cacucci, F., Burgess, N., & O'Keefe, J. (2010). Development of the hippocampal cognitive map in preweanling rats. Science, 328 (5985), 1573-1576. doi:10.1126/science.1188224
Lever, C., Burton, S., Jeewajee, A., Wills, T. J., Cacucci, F., Burgess, N., & O Keefe, J. (2010). Environmental novelty elicits a later theta phase of firing in CA1 but not subiculum. Hippocampus, 20 (2), 229-234.
Jeffery, K. J., & Cacucci, F. (2010). Who moved my cheese (again)?. Nat Neurosci, 13 (8), 911-912. doi:10.1038/nn0810-911
Cacucci, F., Yi, M., Wills, T. J., Chapman, P., & O'Keefe, J. (2008). Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model. Proceedings of the National Academy of Sciences of the United States of America, 105 (22), 7863-7868. doi:10.1073/pnas.0802908105
Cacucci, F., Wills, T. J., Lever, C., Giese, K. P., & O'Keefe, J. (2007). Experience-dependent increase in CA1 place cell spatial information, but not spatial reproducibility, is dependent on the autophosphorylation of the α-isoform of the calcium/calmodulin-dependent protein kinase II. Journal of Neuroscience, 27 (29), 7854-7859. doi:10.1523/JNEUROSCI.1704-07.2007
Wills, T. J., Cacucci, F., Lever, C., Burgess, N., & O'Keefe, J. (2005). Abrupt shift in hippocampal place cell representation from square-like to circle-like in a morph box. Society for Neuroscience, 330.10.
Wills, T. J., Lever, C., Cacucci, F., Burgess, N., & O'Keefe, J. (2005). Attractor dynamics in the hippocampal representation of the local environment. Science, 308 (5723), 873-876. doi:10.1126/science.1108905
Burgess, N., Cacucci, F., Lever, C., & O'Keefe, J. (2005). Characterising multiple independent behavioural correlates of cell firing in freely moving animals. Hippocampus, 15 (2), 149-153.
Wills, T. J., Cacucci, F., Lever, C., Burgess, N., & O'Keefe, J. (2004). Abrupt shift in hippocampal place cell representation from square-like to circle-like in a morph box. Society for Neuroscience Abstracts.
Cacucci, F., Lever, C., Wills, T. J., Burgess, N., & O Keefe, J. (2004). Theta-modulated place-by-direction cells in hippocampal formation in the rat. Journal of Neuroscience, 24 (38), 8265-8277. doi:10.1523/JNEUROSCI.2635-04.2004
Lever, C., Cacucci, F., Wills, T., Burton, S., McClelland, A., Burgess, N., & O'Keefe, J. (2003). Spatial coding in the hippocampal formation: input, information type, plasticity and behaviour. In K. J. Jeffery (Ed.), The Neurobiology of Spatial Behaviour. Oxford: Oxford University Press.
Lever, C., Wills, T., Cacucci, F., Burgess, N., & O'Keefe, J. (2002). Long-term plasticity in the hippocampal place cell representation of environmental geometry. Nature, 416 (6876), 90-94. doi:10.1038/416090a
Lever, C., Burgess, N., Cacucci, F., Hartley, T., & O'Keefe, J. (2002). What can the hippocampal representation of environmental geometry tell us about Hebbian learning?. Biological Cybernetics, 87 (5-6), 356-372.
Hartley, T., Burgess, N., Lever, C., Cacucci, F., & O'Keefe, J. (2000). Modeling place fields in terms of the cortical inputs to the hippocampus. Hippocampus, 10 (4), 369-379. doi:10.1002/1098-1063(2000)10:4<369::AID-HIPO3>3.0.CO;2-0
Cacucci, F., Lever, C., Burgess, N., & O'Keefe, J. (2000). Topodirectional cells in the hippocampal formation of the rat.European Journal of Neuroscience, 12, 86-?.
Lever, C., Cacucci, F., Burgess, N., & O'Keefe, J. (1999). Squaring the circle: place fields do not "remap" between environments which differ only in shape. Society for Neuroscience Abstracts, 24 (556), 2-?.
Pernas-Alonso, R., Schaffner, A. E., Perrone-Capano, C., Orlando, A., Morelli, F., Hansen, C. T., . . . di Porzio, U. (1996). Early upregulation of medium neurofilament gene expression in developing spinal cord of the wobbler mouse mutant. Brain Res Mol Brain Res, 38 (2), 267-275.